Breast Reconstruction with Fat Grafting

What is fat grafting?

Fat grafting is a powerful and effective tool1 that we use with many of our breast reconstruction patients. With fat grafting, we can:

Fat grafting can make a reconstructed breast feel soft, warm, and natural

In mastectomy reconstruction, there is often a step off or an area where the breast contour looks unnatural. The top of an implant may show, the breast may feel cool to the touch, or rippling may be visible through the skin. Fat grafting adds natural thickness using your own body fat2. Fat adds a layer of natural tissue that cannot be achieved by implants alone. Typically, the whole mastectomy area requires some graft, as it improves the skin quality, warmth, and texture. Additional fat can be grafted anywhere there is a divot, a dip, visible implant rippling, or any other area that would benefit. The fat grafting can be done at any time after the mastectomy reconstruction, from 6 months to 60 years. It also has benefits of improved comfort and softness, and gets rid of the feeling some women have of “always wearing a bra” or “feels uncomfortable all the time” that can come with implant based reconstruction.

Fat grafting can create a breast without an implant

For fat grafting as a sole method of reconstruction, first the mastectomy is performed with a small implant that acts as a spacer. Many of our patients that choose this option want to avoid silicone altogether, and we usually use a saline implant for these patients. The space allows the breast to maintain its basic shape without sticking down to the chest wall. The mastectomy can be skin and nipple sparing, with the incision under the breast, to create the best breast appearance. After the area has healed, typically 6 months, the implant size is decreased and the volume is replaced with fat. Each time, between 100 and 400cc of fat is grafted, depending on the volume that is safe for each patient. Eventually, the implant is removed. This may take one session of fat grafting for breasts that are small, and it may take more sessions3 for breasts that are larger. The final breast size does not need to be the same size as the original breast.

Fat grafting can improve breast appearance and symmetry after lumpectomy and radiation

With a lumpectomy, a portion of the breast is removed where the breast cancer is located, and some normal surrounding tissue. Then the remaining breast tissue is radiated to help to prevent recurrence. This leaves the breast smaller, and also tighter and higher than the other breast. The radiated breast can also feel painful, tense and tight, because the radiation not only kills the more rapidly dividing cancer cells but injures the natural repair cells, or stem cells, of the breast. This makes it hard for the breast to fully recover from the radiation itself, as the very cells that repair the radiation defect also are damaged by the radiation. Fat grafting for a radiated lumpectomy not only replaces that lost volume for the lumpectomy, but also places new, safe mesenchymal stem cells that helps heal the damaged tissue.

Dr. Killeen

Dr. Killeen
Breast and Body Plastic and Reconstructive Surgeon

Double-Board-Certified Beverly Hills Plastic Surgeon and Breast & Body Specialist

American Society of Plastic Surgeons
American Board of Plastic Surgery
American College of Surgeons
The Aesthetic Society

Is Fat Grafting Safe?

Fat transfers have been used for twenty years to restore areas of the body affected by illness or injury, or to improve the appearance of certain trouble spots that deflate with age. Successful fat grafting, however, is very technique dependent4. There is a specific way that the fat must be harvested, processed, and transferred successful fat grafting involves moving living from a “harvest site” (area of fat) to a “donor site” (site that needs fat). Each year, our plastic surgeons perform hundreds of breast reconstruction surgeries involving fat grafting.

Dr. Cassileth
Breast Specialist

Board-Certified Beverly Hills Plastic Surgeon, Breast Specialist, and Direct-to-Implant Breast Reconstruction Inventor

American Society of Plastic Surgeons
American Board of Plastic Surgery
American College of Surgeons
The Aesthetic Society
Dr. Cassileth

How Does Fat Grafting for Breast Reconstruction Work?

First, we look at the area that needs the fat grafting, and choose the goal volume to be transferred. Then, we choose a donor site. We choose a site that remains a little fat even when you are then. During the surgery, the fat is taken from your body using low trauma liposuction, which is similar to liposuction but uses lower aspiration pressures. Fat is also often taken in smaller amounts and from more than one area to keep the donor sites normal in appearance (but a little thinner!). Incisions are hidden in natural creases and are approximately 3mm, which is very small. After the fat has been harvested, it is processed and purified. The final fat for transfer is pure solid fat cells placed into many 3cc syringes, where they are placed into the breast using blunt tiny cannulaes that distribute the new living fat cells amongst the normal subcutaneous fat. With each pass of the cannula, only 0.1 – 0.2cc is placed, which keeps the fat in close contact with the perfused tissue. This minimizes the risk of fat necrosis by surrounding the newly placed fat with viable, supportive tissue. This technique is meticulous, taking about 1 hour per 100cc of fat transferred. At each session, the amount of fat in the breast can be doubled, allowing more gain after the first surgery if more than one session is desired.

DR. MIN
Breast Specialist

An Ivy-League-Trained Plastic Surgeon Specializing in Breast and Body Procedures in Los Angeles

Dr. Min

What should I expect from my fat grafting procedure?

With almost no exceptions, fat transfer works. Critical steps, such as minimimizing the fat is outside the body, post-operative support of fat with diet and hyperbaric, small aliquot injection intra-operatively, and minimizing fat trauma, must be followed to the letter each and every time to get results. Remember that fat, however, is limited as to how much can be injected with every surgery. If too much fat is injected, this can also lead to poor blood flow to the newly placed fat and fat necrosis. A good rule of thumb is that patients can expect doubling of their natural fat thickness. This can be frustrating for patients with thin mastectomy flaps, as doubling of thin tissues still does not look like a real breast and allow for implant in one surgery. We will be setting your expectations at a realistic level after your physical exam, as the thickness of the natural tissue can be measured, and by using our Vectra, which allows us to know your exact implant to natural ratio.

You can expect to retain around 80% of the fat transferred into your breast. The fat that does successfully take is permanent. There are no incisions made to the breast. Instead, the small ports are made with a cannula and heal with little or no scar. Patients also benefit by gaining a trimmer, slimmer area of the body from where the fat was harvested.

What is recovery like after fat grafting?

Fat transfer is a relatively straightforward surgery, essentially combining low trauma liposuction with needle free injections. Breasts are pain-free, and the liposuction site is sore for a less than one week. We usually perform the procedure as outpatient, and patients require few or no pain medications. You will be provided with the proper compression garment to minimize swelling of the fat harvest area.

Because the fat transferred to the breast consists of live cells, you will want to avoid any tight compression of the breasts for at least 4 weeks to allow the new cells to become integrated into the existing tissue. You should not sleep on your stomach or any other activity that would put direct pressure on your breasts. No high impact activity is allowed for one month. Most patients find they can return to work in 3-5 days for more sedentary jobs and a week for work that requires more movement.

To find out precisely what fat grafting breast reconstruction options are available to you, and how best to achieve the look that you want, call our office at 310.278.8200 to make an appointment for a consultation, or click here send us a message.


1Seminars in Plastic Surgery. Fat Grafting in Breast Reconstruction. Available:
https://pubmed.ncbi.nlm.nih.gov/32071575 Accessed February 7, 2021.

2The American Society of Breast Surgeons Foundation. Fat Grafting and Breast Reconstruction . Available:
https://breast360.org/topic/2019/06/03/fat-grafting-and-breast-reconstruction Accessed February 7, 2021.

3Journal of Plastic, Reconstructive & Aesthetic Surgery. Efficacy of breast reconstruction with fat grafting: A systematic review and meta-analysis. Available:
https://pubmed.ncbi.nlm.nih.gov/30245019 Accessed February 7, 2021.

4American Society of Plastic Surgeons. Fat Transfer/Fat Graft and Fat Injection - ASPS Guiding Principles. Available:
www.plasticsurgery.org/Documents/medical-professionals/health-policy/guiding-principles/ASPS-Fat-Transfer-Graft-Guiding-Principles.pdf Accessed February 7, 2021.

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